首页 > 范文大全 > 正文

抗生素降阶梯治疗重症肺炎46例临床观察

开篇:润墨网以专业的文秘视角,为您筛选了一篇抗生素降阶梯治疗重症肺炎46例临床观察范文,如需获取更多写作素材,在线客服老师一对一协助。欢迎您的阅读与分享!

【摘要】 目的:研究分析抗生素降A梯治疗对于重症肺炎患者临床治愈率、不良反应及气管插管率的影响。方法:随机选取2015年1月-2016年1月于本院就诊的重症肺炎患者92例,采用随机数字表法分为观察组与对照组,每组46例。对照组患者给予抗生素升级治疗,观察组患者给予抗生素降阶梯治疗,比较两组临床疗效。结果:观察组患者临床治愈率、临床治疗总有效率分别为52.17%、93.48%,均优于对照组的28.26%和78.26%,两组比较差异均有统计学意义(P

【关键词】 抗生素; 降阶梯治疗; 重症肺炎; 不良反应; 气管插管率

Clinical Observation on 46 Cases of Severe Pneumonia Treated by Antibiotic De-escalation Therapy/CAI Jin-liang,LUO Jian-fen,XIE Wen-jie,et al.//Medical Innovation of China,2017,14(16):057-060

【Abstract】 Objective:To study the clinical effect of severe pneumonia treated by antibiotic de-escalation therapy.Method:From January 2015 to January 2016,92 patients with severe pneumonia treated in our hospital were randomly selected and divided into observation group and control group according to the random number table method,46 cases in each group.The control group was treated with antibiotics and upgrading treatment,while the observation group was given the antibiotic de-escalation therapy,the clinical curative effect of the two groups were compared.Result:The clinical cure rate and total efficiency of observation group were respectively 52.17% and 93.48%,they were better than those of the control group’s 28.26%,78.26%,the differences were statistically significant(P

【Key words】 Antibiotics; De-escalation therapy; Severe pneumonia; Adverse reaction; Endotracheal intubation rate

综上所述,采用抗生素降阶梯治疗重症肺炎患者,能够显著提高患者的临床治愈率,降低患者的气管插管率,有效缩短患者的住院时间以及抗生素使用时间,降低不良反应发生率,安全可靠,值得在临床上推广使用。

参考文献

[1]曾宗鼎,邢崇浩.降阶梯方案治疗呼吸科重症监护病房老年重症肺炎患者的临床疗效[J].中国老年学杂志,2014,34(8):2271-2273.

[2]苏文华,贾强,范一木,等.降阶梯疗法在蛛网膜下腔出血合并肺炎的疗效观察[J].中国处方药,2016,14(4):1-3.

[3]中华医学会呼吸病学分会.社区获得性肺炎诊断和治疗指南[J].中华结核和呼吸杂志,2006,29(10):651-655.

[4]贝政平.内科疾病诊断标准[S].2版.北京:科学出版社,2007:725-726.

[5]黄桔红.降阶梯抗生素疗法在治疗慢性阻塞性肺疾病并肺炎的作用[J].医学理论与实践,2013,26(2):183-184.

[6]李华,刘畅.抗生素降阶梯治疗重症肺炎的临床疗效及安全性[J].海南医学,2016,27(11):1773-1775.

[7] Kew J,Rees G L,Close D.Multiplanar reconstructed computed tomography images improves depiction and understanding of the anatomy of the frontal sinus and recess[J].Am J Rhinol,2002,16(2):19-23.

[8] Shelbourne K D,Brueckmann F R.Rush-pin fixation of supracondylar and intercondylar fractures of the femur[J].J Bone Joint Surg Am,1982,64(2):161-169.

[9] Stammberger H R,Kenney D W.Paranasal sinuses:anatomic terminology and nomenclature[J].Ann Otol Rhinol Laryngol Suppl,1995,167:7-16.

[10] W S B,Lee K-F.The agger nasi cell:the key to understanding the an atomy of the frontal recess[J].Otolaryngol Head Neck Surg,2014,12(9):497-507.

[11] Choi B,Lee H J,Han J K,et al.Detection of hypervascular nodular hepatocellur carcinomas:value of triphasichelical CT compared with iodizedoil CT[J].Am J Roentgenol,2013,157(2):219-224

[12]张国春.头孢噻肟钠与头孢他啶治疗感染性肺炎临床效益比较[J].亚太传统医药,2013,9(8):166-167.

[13]行G春.苯唑西林钠治疗金葡菌感染的小儿肺炎的疗效分析[J].健康必读(下旬刊),2013,6(9):43-44.

[14]夏勇,邓长刚,孔渝,等.美罗培南治疗艾滋病合并重症肺炎51例临床对照研究[J].中国药业,2014,(21):22-23.

[15] Chiu A G,Goldstein G H,Kenndy D W.Revision endoscopic frontal sinus surgery[J].Otolaryngol Clin North Am,2011,34(1):77-90.

[16] Koreas G B,bine traditional Chinese and Western medicine clinical results[J].Rev Endocr Metab Disord,2013,73.

[17] Shingu Y,Shiiya N,Ooka T,et al.Augmentation index is elevated in aortic aneurysm and dissection.[J].Annals of Thoracic Surgery,2014,87(5):1373-1377.

[18] Várady E,Feher E,LevaI A,et al.Estimation of vessel age and early diagnose of atherosclerosis in progeria syndrome by using echo-tracking[J].Clinical Hemorheology Microcirculation,2014,44(4):297-301.

[19] Guerin O,Soto M E,Brocker P,et al.Nutritional status assessment during Alzheimer’s disease[J].J Nutr Health Aging,2012,9(2):81-84.

[20] ArakI T,Emoto M,Teramura M,et al.Effect of adiponectin on carotid arterial stiffness in type 2 diabetic patients treated with pioglitazone and metformin[J].Metabolism,2012,55(8):996-1001.

(收稿日期:2017-03-13) (本文编辑:周亚杰)