胞磷胆碱钠片治疗急性脑出血的临床疗效
开篇：润墨网以专业的文秘视角，为您筛选了一篇胞磷胆碱钠片治疗急性脑出血的临床疗效范文，如需获取更多写作素材，在线客服老师一对一协助。欢迎您的阅读与分享！
[摘要] 目的 探讨胞磷胆碱钠片治疗急性脑出血的临床疗效及安全性。 方法 将本院住院治疗的急性脑出血患者178例，随机分成治疗组与对照组各89例。对照组患者采用常规的脑出血治疗，治疗组在对照组治疗基础上给予患者胞磷胆碱钠片治疗。 结果 治疗组与对照组治疗后，神经功能缺损评分均较治疗前有明显改善，但治疗组改善的程度明显大于对照组（P < 0.05）。治疗组89例患者的总有效率为95.51%，对照组89例患者的总有效率为69.66%，两组患者总有效率相比，治疗组明显高于对照组，差异有统计学意义（P < 0.05）。 结论 胞磷胆碱钠片治疗急性脑出血是安全的、有效的，可以有效地改善患者的神经功能，值得在临床广泛推广。
[关键词] 急性脑出血；胞磷胆碱钠片；临床疗效；安全性
[中图分类号] R743.34 [文献标识码] A [文章编号] 1674—4721（2012）09（c）—0060—02
The clinical curative effect of citicoline sodium tablets in the treatment of acute cerebral hemorrhage
QIU Guanyang HUANG Dandan DENG Yaofang WU Yong HUANG Hanning CUI Mingzhi
Department of Neurology， the People''s Hospital of Gaozhou City in Guangdong Province， Gaozhou 525200， China
[Abstract] Objective To discuss the clinical curative effect and safety of citicoline sodium tablets in the treatment of acute cerebral hemorrhage. Methods One hundred and seventy—eight cases of patients with acute cerebral hemorrhage hospitalized in our hospital were randomly divided into treatment group and control group （n = 89）. Patients in control group were given conventional treatment for cerebral hemorrhage. Patients in treatment group were given citicoline sodium tablets on the base of the control group. Results After treatment， the neural function defect scale of the treatment group and control group were obviously improved than before treatment， while the degree of improvement in the treatment group was significantly higher than that in the control group （P < 0.05）. The total effective rate of 89 patients of the treatment group was 95.51%， the total effective rate of 89 patients of the control group was 69.66%， the total effective rate of two groups was compared， and the treatment group was significantly higher than the control group， the difference was statistically significant （P < 0.05）. Conclusion The treatment of citicoline sodium tablets in the treatment of acute cerebral hemorrhage is safe， effective， and can effectively improve patients with neural function， it is worthy of clinical promotion widely.
[Key words] Acute cerebral hemorrhage； Citicoline sodium tablets； Clinical curative effect； Safety
脑出血（ICH）是临床上神经科常见的急性脑血管病，具有很高的病死率和病残率。目前临床上的主要治疗方法为传统的脱水、降颅压、降血压及防治并发症等治疗。脑出血后脑水肿是造成患者脑功能损伤的主要原因，也是脑出血后继发性脑损伤的主要标志[1]。胞磷胆碱（CDP—choline）是合成磷脂酰胆碱过程中的一个中间体，主要在生物膜的形成过程中起到重要的作用，同时还在生物电的传导以及神经介质的转移过程中有着十分明显的作用。笔者为了探讨胞磷胆碱钠片在治疗急性脑出血的临床疗效及安全性，采用胞磷胆碱钠治疗急性脑出血患者89例，取得了满意的效果，现总结报道如下：
1 资料与方法
1.1 一般资料