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【摘要】 目的 观察疏肝调经法治疗月经期复发性口腔溃疡的临床疗效。方法 82例月经期复发性口腔溃疡患者, 随机分为治疗组(42例)和对照组(40例)。治疗组采用基本方柴胡疏肝散加减治疗, 对照组采用服用复合维生素B、维生素C治疗。两组均于经前1周开始服药, 连服3个月经周期, 观察疗效。结果 治疗组经治疗后溃疡面积显著变小于治疗前, 差异有统计学意义(P0.05)。治疗后治疗组溃疡面积小于对照组(P
【关键词】 复发性口腔溃疡;月经期;肝气郁结;疏肝调经法;疗效观察
DOI:10.14163/ki.11-5547/r.2016.33.066
Observation of liver soothing and menstruation regulating method in the treatment of menstrual recurrent oral ulcer ZHANG Hong-xiang, ZHAO Qing-xia. Department of Stomatology, Jinan City Hospital of Traditional Chinese Medicine, Jinan 250012, China
【Abstract】 Objective To observe curative effect by liver soothing and menstruation regulating method in the treatment of menstrual recurrent oral ulcer. Methods A total of 82 patients with menstrual recurrent oral ulcer were randomly divided into treatment group (42 cases) and control group (40 cases). The treatment group received basic prescription of Chaihu Shugan powder for modified treatment, and the control group received vitamin B and vitamin C for treatment. Both groups received medicine in 1 week before menstruation for 3 menstrual cycles, and their curative effects were observed. Results The treatment group had much smaller ulcer area after treatment than those before treatment, and the difference had statistical significance (P0.05). The treatment group had smaller ulcer area than the control group(P
【Key words】 Recurrent oral ulcer; Menstrual; Stagnation of liver qi; Liver soothing and menstruation regulating method; Observation of curative effect
头⑿钥谇焕Q瘢recurrent oral ulcer, ROU) 是最常见的口腔黏膜病, 在普通人群中发病率高达20%, 根据溃疡的多少、大小、深浅等可分为:轻型、重型、疱疹样溃疡[1]。其中轻型口腔溃疡约占80%, 该病具有周期性复发的规律, 溃疡直径为2~4 mm, 多为圆形和椭圆形, 孤立存在, 每次1~5个不等。复发性口腔溃疡整个发作期持续1~2周, 有自限性, 愈后不留瘢痕。发病时有明显的烧灼感, 影响语言及进食。严重者降低患者生活质量, 影响语言及进食[2]。该病可能与内分泌变化、胃肠功能障碍、变态反应、局部刺激和精神因素等有密切关系; 女性多于男性, 尤其在青中年女性的经期及月经前后出现。反复口腔溃疡与月经期有关的口腔溃疡, 中医称为“行经口糜”[3]。女性患者在经前、经期发病, 每月如期发作, 经净则渐愈, 复发性口腔溃疡病因目前尚不明确, 对该病的临床治疗是以对症和局部治疗为主, 只是具有一定的短期疗效。中医强调辨证论治和整体思想对治疗该病有较大优势[4]。作者经过多年的临床观察, 认为本病证属肝气郁结, 治疗宜疏肝理气。在临床上从肝脏入手治疗月经期口腔溃疡, 取得良好的疗效, 现报告如下。