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分析纳洛酮及无创呼吸机在老年慢性阻塞性肺疾病伴呼吸衰竭治疗中的临床效果

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[摘要] 目的 分析纳洛酮无创呼吸机老年慢性阻塞性肺疾病呼吸衰竭治疗中的应用效果。 方法 随机选取该院2013年4月―2014年4月收治的老年慢性阻塞性肺疾病伴呼吸衰竭患者60例,将其随机分为两组,即对照组与观察组,每组各30例,分别采用无创呼吸机、纳洛酮联合无创呼吸机进行治疗,比较两组患者临床疗效。 结果 对照组治疗总有效率为76.67%,观察组为96.67%,对照组无效率为23.33%,观察组为3.33%,差异有统计学意义(P

[关键词] 纳洛酮;无创呼吸机;老年慢性阻塞性肺疾病;临床疗效

[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742(2016)01(a)-0074-02

Clinical Effect Analysis of Naloxone and Non-invasive Ventilator in the Treatment of Elderly Patients with Chronic Obstructive Pulmonary Disease with Respiratory Failure

DUAN Wen-hua

Fifth Clinical Medical School of Fujian University of traditional Chinese Medicine(Sanming Second Hospital of Fujian Province),Sanming, Fujian Province,365000 China

[Abstract] Objective To analyze the application effect of naloxone and non-invasive ventilator in the treatment of elderly patients with chronic obstructive pulmonary disease with respiratory failure. Methods 60 cases of elderly patients with chronic obstructive pulmonary disease with respiratory failure treated in our hospital from April 2013 to April 2014 were selected and randomly divided into two groups with 30 cases in each, the control group were given non-invasive ventilator treatment, the observation group were given naloxone and non-invasive ventilator treatment, the clinical curative effects of the two groups were compared. Results The total treatment effective rate was 76.67% in the control group and 96.67% in the observation group, the inefficiency rate was 23.33% in the control group and 3.33% in the observation group, and the differences were obvious and were statistically significant(P

[Key words] Naloxone; Non-invasive Ventilator; Elderly patients with chronic obstructive pulmonary disease; Clinical curative effect

慢性阻塞性肺疾病是一种慢性消耗性疾病,在临床上,常多发于老年人。该病在发展过程中,严重影响患者的肺功能,另外再加上肺部感染等影响,极易并发呼吸功能衰竭,在得不到及时、有效的处理时,将直接造成患者死亡[1]。该研究对该院2013年4月―2014年4月收治的老年慢性阻塞性肺疾病伴呼吸衰竭患者60例,采取纳洛酮及无创呼吸机进行治疗,该将研究纳洛酮及无创呼吸机在老年慢性阻塞性肺疾病伴呼吸衰竭治疗中的应用效果,现报道如下。

1 资料与方法

1.1 一般资料

随机选取的对象是2013年4月―2014年4月来该院治疗老年慢性阻塞性肺疾病伴呼吸衰竭的患者60例。经检查,所有患者均符合老年慢性阻塞性肺疾病伴呼吸衰竭临床诊断标准,无对研究药物过敏者。随机将其分为观察组和对照组,每组各30例,其中观察组男17例,女13例,年龄61~83岁,平均年龄(71.5±8.7)岁,病程2~14年,平均病程(8.5±3.6)年;对照组男19例,女11例,年龄63~81岁,平均年龄(70.4±5.6)岁,病程2~13年,平均病程(8.2±2.9)年。两组患者基本资料(年龄、性别、病程等)比较差异无统计学意义(P>0.05),具有可比性。

1.2 治疗方法

所有患者均给予慢性阻塞性肺疾病伴呼吸衰竭基础治疗,包括检测患者持续心率、血压、血氧饱和度,经2013(11):66-67.

(收稿日期:2015-10-10)