慢性前列腺炎与男性不育症的相关性研究
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[摘要] 目的 探讨慢性前列腺炎与男性不育症的相关性。 方法 选取本院2010年3月～2012年5月收治的男性不育症患者103例，均行前列腺液常规检测和支原体培养，根据检测结果分为两组，非慢性前列腺炎患者47例为对照组，慢性前列腺炎患者56例为观察组，分别检测患者的参数（液化时间）、活力及畸形情况，分析慢性前列腺炎与男性不育症相关因素的关系。 结果 观察组密度、a+b活力、活动率均明显低于对照组，观察组液化时间、畸形率均明显高于对照组，差异有统计学意义（P ＜ 0.05）。慢性前列腺炎与密度、a+b活力、活动率均具有一定负相关性（P ＜ 0.05），慢性前列腺炎与液化时间、畸形率均具有一定正相关性（P ＜ 0.05）。 结论 慢性前列腺炎可延长患者的液化时间，降低活力，对患者的质量产生影响，是男性不育症的诱发原因之一。
[关键词] 慢性前列腺炎；男性不育症；相关性研究
[中图分类号] R697.33 [文献标识码] A [文章编号] 1673-7210（2012）08（c）-0046-02
Correlation research between chronic prostatitis and male infertility
RAO Liqiang LIAO Jinxian YE Xiangyang YU Xiang GAO Caifeng
Department of Urology Surgery, the Center People's Hospital of Huizhou City, Guangdong Province, Huizhou 516001, China
[Abstract] Objectives To investigate the correlation between chronic prostatitis and male infertility. Methods 103 patients with male infertility were selected in our hospital from March 2010 to May 2012. All patients were underwent prostate liquid conventional detection and semen mycoplasma culture. According to detection results, patients were divided into two groups. 47 patients without chronic prostatitis were divided into the control group; 56 patients with chronic prostatitis were divided into the observation group. Semen parameters ( liquefied time ), vitality of sperm, sperm deformity were detected. The correlation between related factors of male infertility and chronic prostatitis were analyzed. Results The sperm density, sperm a+b activity, sperm motility in the observation group were significantly lower than those in the control group; then the semen liquefaction time, sperm malformation rate in the observation group were significantly higher than those in the control group, the differences were statistically significant (P < 0.05). Chronic prostatitis was negatively correlated with sperm density, sperm a+b activity, sperm motility, which was positively correlated with semen liquefaction time, sperm malformation rate (P ＜ 0.05). Conclusion Chronic prostatitis can prolong the semen liquefaction time and reduce the vitality of sperm, which can also affect semen quality of patients. Chronic prostatitis is one of induce reasons for male infertility.
[Key words] Chronic prostatitis; Male infertility; Correlation study
慢性前列腺炎是男性较为常见的一种生殖疾病，发病率为5%～50%，严重影响着患者的生活质量和生殖健康[1-3]。男性不育症也是临床上较为常见的一种生殖疾病，据WHO调查，15%的育龄夫妇存在不育问题，其中，男方因素占40%[4-6]。有研究表明，慢性前列腺炎对男性的生殖状况具有一定影响[7-9]。为了探讨慢性前列腺炎与男性不育症的相关性，笔者选取2010年3月～2012年5月本院收治的男性不育症患者103例，根据是否患有慢性前列腺炎分为两组进行分析研究，现报道如下：