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血糖控制应用于妊娠期糖尿病对妊娠结局的影响评价

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[摘要] 目的 探究血糖控制应用于妊娠期糖尿病妊娠结局影响评价。方法 资料随机选自2011年2月―2012年2月在该院诊治的妊娠糖尿病患者180例,将患者依照治疗后血糖的控制程度分为两组,血糖满意控制145例作对研究组,血糖不满意控制35例作对照组,同期检查的健康孕妇60例作参照组,分析3组的母婴妊娠结局情况。结果 研究组的孕妇剖宫产、产后出血、羊水过多、胎膜早破等并发症,以及巨大儿、新生儿的窒息等并发症情况,与对照组比较发生较少,差异有统计学意义(P0.05)。结论 对于妊娠期糖尿病予以有效满意的血糖控制,能有效改善母婴妊娠结局,具有一定临床应用价值。

[关键词] 血糖控制;妊娠期糖尿病;妊娠结局;影响

[中图分类号] R714 [文献标识码] A [文章编号] 1674-0742(2014)05(c)-0037-02

[Abstract] Objective To explore the impact of glycemic control applied to gestational diabetes on pregnancy outcome. Methods The data of 180 cases of patients with gestational diabetes diagnosed and treated in our hospital from February, 2011 to February, 2012 were randomly selected. According to the degree of controlling blood glucose after treatment, the patients were divided into two groups, 145 cases with satisfactory control of blood glucose were selected as the study group, and 35 cases with dissatisfied control of blood glucose as the control group. And 60 cases of healthy pregnant women underwent examinations during the same period were selected as the reference group. The outcome of pregnancy of three groups was analyzed. Results Compared with the control group, the complications such as cesarean section, postpartum hemorrhage, hydramnion, premature rupture of membranes, macrosomia, newborn asphyxia and so on occurred in the study group were less than those occurred in the control group, the differences were statistically significant(P0.05). Conclusion Satisfactory controlling the blood glucose of patients with gestational diabetes can effectively improve the outcome of maternity and infant with certain clinical application value.

[Key words] Glycemic control; Gestational diabetes; Pregnancy outcome; Impact

妊娠期的糖尿病指孕妇在妊娠期间第一次出现糖耐量的减损,当孕妇分娩以后机体的血糖正常恢复。妊娠期糖尿病属于临床产科常见妊娠期的并发症,此病发生对于母婴妊娠结局负面影响非常大。妊娠期糖尿病患者由于血糖控制不理想,可并发血管性的病变,造成孕妇妊娠高血压的发病率比较高,甚至会出现胎膜早破、新生儿早产等并发症。因此,重视孕妇妊娠期间血糖的有效控制一直属于临床产科研究的重要课题。为探究血糖控制应用于妊娠期糖尿病对妊娠结局的影响评价。现对2011年2月―2012年2月在该院诊治的180例妊娠糖尿病血患者予以血糖控制后对母婴妊娠结局的影响进行分析,报道如下。

1 资料与方法

1.1 一般资料

选取在该院诊治的妊娠糖尿病患者180例,年龄22~33岁,平均年龄(27±5.73)岁,将患者依照治疗后血糖的控制程度分为两组,血糖满意控制145例作对研究组,予以血糖不满意控制35例作对照组。同期检查的健康孕妇60例作参照组,年龄23~35岁,平均年龄(28±5.91)岁。

1.2 诊断标准

诊断标准:空腹时的血糖检测2次高于或等于5.8 mmol/L,或经过OGTT(空腹5.6 mmol/L,1 h10.3 mmol/L,2 h8.6 mmol/L)的试验血糖值2项以上(包括2项)达到或是超过正常值,可诊断为妊娠期糖尿病[1]。

1.3 纳入和排除标准