首页 > 范文大全 > 正文

“温药和之”在治疗支气管扩张缓解期中的应用

开篇:润墨网以专业的文秘视角,为您筛选了一篇“温药和之”在治疗支气管扩张缓解期中的应用范文,如需获取更多写作素材,在线客服老师一对一协助。欢迎您的阅读与分享!

[摘要] 目的 观察中药以“温药和之”之法与西药盐酸氨溴索口服治疗支气管扩张缓解期的作用。 方法 将46例支气管扩张患者随机分为治疗组(24例)和对照组(22例),治疗组内服中药汤剂,1剂/d;对照组口服盐酸氨溴片,30 mg/次,3次/d。两组疗程均为30 d。 结果 治疗后治疗组中医症状积分明显减少(P < 0.05);治疗组总有效率为91.7%,对照组为54.5%,两组比较差异有统计学意义(P < 0.05)。 结论 以温阳宣通之法治疗支扩缓解期对于减少痰液生成,缓解症状,增强体质,疗效确切,对减少复发有积极作用。

[关键词] 温药;痰饮;支气管扩张

[中图分类号] R256.1 [文献标识码] A [文章编号] 1673-7210(2012)08(b)-0110-02

The application of “Wen Yao He Zhi” method in the treatment of bronchiectasis in remission stage

PU Rong LI Tao QIU Lin

Department of Respiratory, the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Sichuan Province, Chengdu 610072, China

[Abstract] Objective To observe the influence on "Wen Yao He Zhi" method of traditional Chinese medicine and oral Ambroxol Hydrochloride in the treatment of bronchiectasis in remission stage. Methods 46 patients with bronchiectasis were randomly divided into treatment group (24 cases) and control group (22 cases). The treatment group was given Chinese medicine for 1 dose a day while the control group was given 30 mg of Ambroxol Hydrochloride for 3 times a day. 30 days were one period of treatment for both groups. Results TCM syndrome score in treatment group decreased significantly (P < 0.05); the total effective rate of treatment group was 91.7% while the control group's was 54.5%, there were significant differences between two groups (P < 0.05). Conclusion It is really effective that using the method of warming yang and transporting qi can reduce sputum and relieve symptoms for bronchiectasis in remission stage, and even enhance physique as well, furthermore, it also has a positive effect to reduce relapse of bronchiectasis.

[Key words] Warm herbs; Phlegm-fluid retention; Bronchiectasis

支气管扩张(以下简称“支扩”)在形态上是指支气管不可逆的扩张和管壁的增厚。临床以慢性咳嗽,咳大量脓痰和(或)反复咯血为特征。反复感染、气道阻塞、支气管引流功能损害和防御功能的缺损互为因果,导致支气管损害进行性加重,形成恶性循环,最终导致肺心病和呼吸衰竭[1]。因此,减少反复感染是改善预后的关键,目前西医急性期以抗感染治疗为主,反复发作之势仍难以控制。根据“治未病”的中医理论,故在缓解期治疗非常重要[2],西医对于慢性缓解期则无计可施[3],而中医药就突显出独特的优势。支扩患者以持续咳痰为最苦,故笔者将张仲景《金匮要略》中“病痰饮者,当以温药和之”的理论推广演绎用于支扩缓解期,取得满意疗效,现报道如下:

1 资料与方法

1.1 一般资料

46例支气管扩张患者均来源于2009年6月~2011年8月我院门诊,将患者随机分为治疗组(24例)和对照组(22例),两组患者治疗前一般资料比较差异无统计学意义(P > 0.05),具有可比性。见表1。

1.2 诊断标准

西医诊断标准:参照《实用内科学》诊断标准[1]。中医证候诊断及分级量化标准:《参照中药新药临床研究指导原则(试行)》[4]及《中医内科学》[5]相关内容拟定。主症:咳嗽、咯痰。分无、轻、中、重4级,分别记0、2、4、6分;次症:乏力、恶风、胸闷、纳呆、畏寒。分无、轻、中、重4级,分别记0、2、4、6分;肺部啰音按轻、中、重分别记1、2、3分;舌脉(不记分):舌质淡或暗,苔白腻或黄腻,脉细或滑。以上主症必备,次症2项或2项以上。

1.3 纳入和排除标准

符合西医诊断标准及中医症侯诊断标准,年龄56~70岁,并排除:①结核或肿瘤所致的慢性肺部感染患者;②合并肝、肾、造血系统等严重原发性疾病者;③痰热证侯明显或有出血倾向者。