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摘 要 目的:观察低分子肝素钙联合疏血通治疗下肢深静脉血栓的临床效果。方法:将76例患者分为低分子肝素钙联合疏血通注射液的治疗组(简称治疗组),和单独低分子肝素钙治疗组(对照组)。评估患者治疗后临床疗效的改善情况。结果:干预后,治疗组痊愈14例,显效20例,无效4例,总有效率为89.47%;对照组痊愈12例,显效17例,无效9例,总有效率为76.32%。两组总有效率比较,治疗组优于对照组,差异具有统计学意义(P
关键词 下肢深静脉血栓形成 低分子肝素 疏血通 疗效
中图分类号:R654.3 文献标识码:A 文章编号:1006-1533(2012)20-0033-03
Clinical observation of the efficacy of the low molecular weight heparin combined with ShuXueTong in the treatment of the acute deep venous thrombosis of the lower limbs
GAO Lei, GUO Da-qiao, YAN Hua
(1. Huajing Community Health Service Center in Xuhui District, Shanghai 200231, China;
2. Zhongshan Hospital, Fudan University, Shanghai 200032, China)
ABSTRACT Objective: To observe the clinical efficacy of the low molecular weight heparin calcium combined with ShuXieTong in the treatment of the deep venous thrombosis of the lower limbs. Method: Seventy six patients were divided into the low molecular weight heparin calcium combined with ShuXieTong injection treatment group ( treatment group), and low molecular weight heparin calcium treatment group (control group) according to the principle of randomized control. The patients were evaluated with the clinical efficacy and clotting index improvement. Result: After intervention, in the treatment group 14 cases were cured, 20 cases were improved effectively and 4 cases had no efficacy, in which the total effective rate was 89.47%. In the control group 12 cases were healed, 17cases were markedly improved, and 9 cases failed, in which total effective rate was 76.32%. To compare the two group total effectiveness, the efficacy of the treatment group was more superior than that of the control group and the difference had statistical significance (P< 0.05). Conclusion: Low molecular weight heparin calcium combined with ShuXieTong for the treatment of the deep venous thrombosis of the lower limbs not only has definite treatment efficacy, but also increases blood perfusion to the local blood clots for preventing the disease progression further.
KEY WORDS deep vein thrombosis of the lower limbs; low molecular weight heparin;;ShuXieTong; efficacy
下肢深静脉血栓形成(Deep vein thrombosis, DVT)属于临床常见疾病之一,主要临床表现为单侧下肢的突然肿胀。近年来,该病的发病率在我国呈现不断上升的趋势,患者若急性期治疗不及时,极易引发肺栓塞,从而导致患者的致死率较高[1],已成为严重影响我国人民健康的主要疾患之一。因此,探寻早期诊断和治疗的方法,改善其预后,是目前医护人员需要解决的问题。
选择我中心与复旦大学附属中山医院血管外科自2011年1月-2012年1月联合收治的76例下肢深静脉血栓患者,分别予以低分子肝素钙联合疏血通注射液综合治疗及单独低分子肝素钙治疗,以期探讨最佳的治疗方法,现将临床资料整理回顾分析如下。