宫颈糜烂微波治疗临床观察

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[摘要] 目的 探讨宫颈糜烂微波治疗效果。方法 选择98例宫颈糜烂患者，随机分为两组，各49例。观察组查白带常规，做支原体（UU）、衣原体（CT）培养，后者任一项或两项阳性者，给予口服阿奇霉素再做微波治疗；对照组只查白带常规。两组均于月经干净后3-7d行微波治疗，比较两组疗效。结果 观察组有效率明显高于对照组。结论 宫颈糜烂先常规筛选UU及CT，对阳性者行药物治疗后再给予微波治疗能提高治疗效果。

[关键词] 宫颈糜烂；支原体感染；衣原体感染；微波治疗

doi：10.3969/j.issn.1004-7484（x）.2014.03.296 文章编号：1004-7484（2014）-03-1442-02

宫颈糜烂是已婚妇女的常见疾病和多发病，积极防治并将诊治质量提高到新水平，对早期防治宫颈癌有重要意义。微波治疗是目前宫颈糜烂的有效治疗措施，但有少数患者治疗效果不理想。本文检测了49例宫颈糜烂患者UU及CT感染情况，并对阳性者实施相应治疗，现将结果报道如下。

1 资料和方法

1.1 一般资料 选择2011年7月――2013年1月在我院妇科门诊就诊的宫颈糜烂患者98例，年龄22-55岁。随机分为两组，每组轻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度糜烂7例，中度糜烂20例，重度糜烂22例。观察组微波治疗前查白带常规，并行CT及UU治疗培养，对照组只查白带常规。

1.2 方法

1.2.1 CT，UU检查方法 在窥阴器暴露下，先擦去宫颈管口过多的分泌物，将无菌棉签插入宫颈管口，旋转数周并保留10s，取出放入试管内，直接送检验，行UU及CT培养。

1.2.2 治疗方法 观察组微波治疗前先对CT及UU阳性者给予口服阿奇霉素，0.5g/次，1次/d，空腹或餐后2h服用，连服5d，首剂1g口服[1]，然后于月经干净后3-7d行微波治疗。对照组于月经干净后3-7d直接行微波治疗。禁3个月，微波治疗后60d复查。

1.3 疗效判定标准 治愈：症状消失，宫颈糜烂面消失，宫颈光滑；有效：症状消失，宫颈糜烂面缩小1/2；无效：症状与体征无改变。

1.4 统计学处理 计数资料用X2检验。

2 结 果

2.1 观察组CT及UU阳性情况 见表1。

3 讨 论

宫颈糜烂是已婚妇女的常见病，宫颈微波治疗通过破坏宫颈受损上皮，使之坏死脱落，从而促使新生鳞状上皮覆盖而治愈。近年来，妇女生殖道沙眼衣原体和支原体感染呈上升趋势，CT及UU是两种特殊的病原体。CT具有与革兰阳性细菌相似的细胞壁、DNA及RNA，易侵犯由柱状上皮细胞被覆的组织及器官，包括巴氏腺、尿道、宫颈管、输尿管等，是西方发达国家性传播疾病（STD）的主要病原体之一。UU没有固定形态，只有3层细胞膜，可分布于上皮细胞内，在下生殖道中UU可与致病菌或条件致病菌同时存在。宫颈是CT及UU共同侵犯的场所，CT及UU也是宫颈炎的主要病原体之一，本文CT阳性率为40.82%，UU阳性率为44.90%，与文献报道结果相近。微波治疗后，坏死组织出血，分泌物增多，均为病原体提供了很好的培养基。支原体、沙眼衣原体可通过其特殊结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梗皆谒拗飨赴诜敝常颖芑宓拿庖吲懦猓辗⒀字斐煞锤闯中腥荆贾伦橹苹担焕谒鹕松掀せ指粗斡2]。宫颈支原体、衣原体感染不仅与宫颈糜烂高度相关，而且可以影响宫颈糜烂微波治疗的效果。目前宫颈糜烂微波治疗把宫颈癌及细菌、真菌感染作为术前必查项目，而忽略了隐性解脲支原体和沙眼衣原体的检测，建议对宫颈糜烂患者要考虑是否有支原体、衣原体感染的可能性，并通过有效药物积极治疗感染，配合微波，可有效提高治愈率。

本文观察组中CT及UU阳性者给予口服阿奇霉素治疗后再用微波治疗，其有效率高于单纯微波治疗组，因支原体和衣原体无细胞壁，对影响胞浆蛋白质合成的抗生素敏感，阿奇霉素是大环内脂类药，符合要求，口服阿奇霉素治疗CT及UU感染有效，可阻断宫颈糜烂的进一步发展，经微波治疗后，可促使宫颈上皮生长，达到治愈目的，因此，宫颈糜烂患者微波治疗前应常规筛查UU及CT，并对阳性者给予相应治疗，以提高治疗效果。

参考文献

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